Chapter 3.4 Joint Assessment of White Matter Integrity, Cortical and Subcortical Atrophy to Distinguish Ad from Behavioral Variant Ftd: a Two- Center Study
نویسندگان
چکیده
1 Alzheimer Center & Department of Neurology, Neuroscience Campus Amsterdam, VU University Medical Center, Amsterdam, the Netherlands, 2 Institute of Psychology, Leiden University, Leiden, the Netherlands, 3 Department of Radiology, Leiden University Medical Center, Leiden, the Netherlands, 4 Leiden Institute for Brain and Cognition, Leiden University, Leiden, the Netherlands, 5 Department of Clinical Genetics, Neuroscience Campus Amsterdam, VU University Medical Center, Amsterdam, the Netherlands, 6 Department of Neurology, Erasmus Medical Center, Rotterdam, the Netherlands, 7 Department of Radiology & Nuclear Medicine, Neuroscience Campus Amsterdam, VU University Medical Center, Amsterdam, the Netherlands, 8 Department of Physics & Medical Technology, Neuroscience Campus Amsterdam, VU University Medical Center, Amsterdam, the Netherlands, 9 Department of Epidemiology & Biostatistics, Neuroscience Campus Amsterdam, VU University Medical Center, Amsterdam, the Netherlands.
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Joint assessment of white matter integrity, cortical and subcortical atrophy to distinguish AD from behavioral variant FTD: A two-center study
We investigated the ability of cortical and subcortical gray matter (GM) atrophy in combination with white matter (WM) integrity to distinguish behavioral variant frontotemporal dementia (bvFTD) from Alzheimer's disease (AD) and from controls using voxel-based morphometry, subcortical structure segmentation, and tract-based spatial statistics. To determine which combination of MR markers differ...
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